Nanosized TiO2-Induced Reproductive System Dysfunction and Its Mechanism in Female Mice

Nanosized TiO2-Induced Reproductive System Dysfunction and Its Mechanism in Female Mice

Recent studies have demonstrated nanosized titanium dioxide (nano-TiO2)-induced fertility reduction and ovary injury in animals. To better understand how nano-TiO2 act in mice, female mice were exposed to 2.5, 5, and 10 mg/kg nano-TiO2 by intragastric administration for 90 consecutive days; the ovary injuries, fertility, hormone levels, and inflammation-related or follicular atresia-related cyt...

Sulpiride-Induced Hyperprolactinemia in Mature Female Rats: Evidence for Alterations in The Reproductive System, Pituitary and Ovarian Hormones

Modulatory role of nitric oxide releasing NSAIDs in aging- and lipopolysaccharide-induced cognitive dysfunction in mice

Inflammatory processes play a critical role in the pathogenesis of the neurodegenerative disorders and are associated with cognitive impairments. Nonsteroidal anti-inflammatory drugs (NSAIDs) and nitric oxide releasing NSAIDs are reported to be effective in reducing the risk of developing AD or cognitive impairments. Present experiments were performed to study the possible effect of nitro napro...

Changes in Reproductive Hormones Secretion Involved in Quantum Dots-induced Reproductive Toxicity in Adult Male Mice

Background and Aims: Quantum dots (QDs), as colloidal nanocrystalline semiconductors, present QD wavelengths in terms of biomedical assays and imaging, though the high toxicity of their core demands to be taken into consideration. Investigating this subject is taken into account as an important concept   concerning use of these nanoparticles in the medical applications. Materials a...

Modulatory role of nitric oxide releasing NSAIDs in aging- and lipopolysaccharide-induced cognitive dysfunction in mice

Inflammatory processes play a critical role in the pathogenesis of the neurodegenerative disorders and are associated with cognitive impairments. Nonsteroidal anti-inflammatory drugs (NSAIDs) and nitric oxide releasing NSAIDs are reported to be effective in reducing the risk of developing AD or cognitive impairments. Present experiments were performed to study the possible effect of nitro napro...